A child with PFAPA syndrome complicated by pityriasis lichenoides et varioliformis acuta.
Iba Y, Sugimoto K, Sakata N, Kawada A, Takemura T
Pediatric dermatology •
We encountered a boy with periodic fever, aphthous-stomatitis, pharyngitis, adenitis syndrome, complicated by a papular rash representing pityriasis lichenoides et varioliformis acuta. Proinflammatory cytokines have been implicated in both diseases and may represent the underlying common immunologic mechanism causing the two diseases.